Acknowledgements We thank the University of Maryland Electron Microscopy Core Imaging Facility for transmission electron microscopy consultation and training, Nagendra Yadava and Brandon Carter-Cooper at the University of Maryland Translational Laboratory Shared Service for respirometry consultation, the Ndufa1 antibody, and recombinant perfringolysin O, Amanda Law for shared equipment, Victoria Meadows, Jessica Fluharty, Henry Haller, Erin Weinhold, and Peter Moon for technical assistance, and Scott Thompson for editorial feedback
Current 5-Amino-1MQ research involves mice
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Lastly, the significance of GpoA in virulence was demonstrated using a murine infection model
long-term human safety data remain limited
0.16 ng/ml/12 ml/day till the sacrifice) and intragastrically after cuprizone instilations, while controls received simultaneously drinking water only (12 ml/day) as well as an equivolume of saline (5 ml/kg) intragastrically after cuprizone instillations